Abstract:Protein kinases (PKs) and transcription factors (TFs) are important components of signal transduction, which are involved in the secondary growth of stems. To explore their expression changes in stem secondary growth of albino Artocarpus heterophyllus seedlings, the differentially expressed genes (DEGs) of PKs and TFs were predicted and classified based on transcriptome data, and phylogenetic trees were constructed for 2 PKs and 4 TFs families. The results show that the number of up- and down-regulated DEGs in the receptor-like cytoplasmic kinase (RLCK)-VIII family was 4 each. All of DEGs in Xa and Xb-2 branches in leucine-rich repeat receptor kinase (LRR-RLk)-X family were down-regulated, while those in Xb-1 branch were up-regulated. Among 20 DEGs in TCP family, 15 were up-regulated in AAS. And most genes in zf-HD and GRF families were up-regulated, while all DEGs in Alfin-like were down-regulated in AAS. Therefore, it was suggested that six families might play an important role in the secondary growth of A. heterophyllus stems and the response to abiotic stress.