Abstract:Ligustri Lucidi Fructus is the dried fruits of Ligustrum lucidum, belonging to Oleaceae, which is a traditional Chinese medicine with the effects on nourishing liver and kidney, improving eyesight and hair-blacking. Ligustri Lucidi Fructus contains triterpenoids, iridoids, phenylethanoid glycosides and flavonoids, etc. Many pharmacological studies had shown that it has anti-tumor, antioxidant, anti-inflammatory and analgesic, hepato- protective, antiosteoporosis, immunomodulatory, hypoglycemic and hypolipidemic, antibacterial and antiviral activities. The chemical constituents, pharmacological effects and pharmacokinetics of Ligustri Lucidi Fructus were reviewed, which would provide reference for further development and utilization of Ligustri Lucidi Fructus in China.