Abstract:Twelve nitrogen-containing heterocycles were isolated from the solid cultures of Metarhizium sp. SC0924. On the basis of spectral data, they were identified as cyclo-(Ala-Pro) (1), cyclo-(Pro-Tyr) (2), cyclo-(Val-Leu) (3), cyclo-(Leu-Ile) (4), adenine (5), adenosine (6), uracil (7), thymine (8), thymidine (9), 4-acetyl-aminoimidazole (10), n-butyl pyroglumate (11), and lumichrome (12). Compounds 2 and 3 showed weak antifungal activities against Peronophythora litchii by the agar diffusion method with paper disks.