Abstract:Manglietia longipedunculata, an evergreen broad-leaved plant belonging to the genus Manglietia of the Magnoliaceae family, has only been found in one population in the Nankunshan Provincial Nature Reserve in Longmen City, Guangdong Province. It was currently classified as critically endangered (CR). In this study, the petroleum ether fraction, ethyl acetate fraction, n-butanol fraction and water fraction from stems and leaves were obtained by solvent extraction. The anti-tumor, antioxidant and anti-inflammatory activities of different fractions were evaluated using multiple biological activity test models. The results showed that the petroleum ether fraction of the stems and leaves had the best anti-tumor activity, followed by the ethyl acetate fraction, while the n-butanol and water fractions had almost no anti-tumor activity. The petroleum ether fraction of the stems and leaves had the best anti-inflammatory activity, with IC50 values of (7.20±0.22) and (14.96±0.61) µg/mL, respectively. The ethyl acetate fraction of the stems and leaves had the best antioxidant activity, with IC50 values of (5.12±0.13) and (0.46±0.09) µg/mL, respectively. The functions of its stem and leaf extracts were evaluated at the first time, which could provide a material basis and theoretical support for its later development and utilization.
