Home > Archive>Volume 32, Issue 3, 2024 >446-450. DOI:10.11926/jtsb.4760
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One New Picrotoxane-type Sesquiterpene from Dendrobium nobile
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    Abstract:

    In order to study the chemical constituents in butanol fraction of ethanol extract of Dendrobium nobile, column chromatographic techniques including silica gel, Sephadex LH-20, revised silica gel and HPLC were used to separate the compounds, and spectroscopic techniques including NMR and MS were implied to determine the structures. Totally 3 compounds were isolated, and their structures were identified as 2,11-epoxy-11,13-dihydro-xypicrotoxano-3(15)-lactone (1), 2,4,6-trimethoxyphenol-1-O-β-d-glycoside (2), 3-methylbutan-1-ol β-d-gluco-pyranoside (3). Compound 1 was a new picrotoxane-type sesquiterpene, which is one of the representative components in D. nobile. However, none of the compounds showedα-glucosidase and tyrosinase inhibitory activity, none of them showed activity, and compound 1 show no neuroprotective activity either.

    Reference
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杜国鑫,蔡彩虹,夏益华,黄圣卓,梅文莉,戴好富,陈惠琴.金钗石斛中一个新的木防己毒烷型倍半萜[J].热带亚热带植物学报,2024,32(3):446~450

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History
  • Received:December 01,2022
  • Revised:April 18,2023
  • Online: June 04,2024
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