Home > Archive>Volume 31, Issue 5, 2023 >741-746. DOI:10.11926/jtsb.4650
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Study on Secondary Metabolites of Endophytic Fungus Ogataea sp. RW-S10 from the Pogostemon cablin
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Key Research and Development Plan Projects of Hainan Province (Grant No. ZDYF2021SHFZ075), the Ministry of Finance and the Ministry of Agriculture and Rural Affairs of the National Modern Agricultural Industrial Technology System Special Project (Grant No. CARS-21), the Financial Special Project of the Ministry of Agriculture and Rural Affairs (Grant No. NFZX2021), and the Chinese Academy of Tropical Agricultural Sciences basic Scientific Research Business Expenses Special Project (Grant No. 1630052022030).

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    Abstract:

    In order to obtain bioactive metabolites from Pogostemon cablin endophytic fungus, seven secondary metabolites were isolated and purified from the patchouli endophytic fungus Ogataea sp. RW-S10 by various chromatographic column techniques. Based on spectral data, their structures were identified as ogataearin (1), phenylalaninol (2), parahydroxyacet-ophenone (3), bis(dethio)bis(methylsulfanyl)gliotoxin (4), N-phenylethyl acetamide (5), lumichrome (6), and dehydroxypaxilline (7). Compound 1 was a new compound and showed α-glucosidase inhibitory activity with IC50 value of 39.38 μmol/L.

    Reference
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阮武,郭教岑,马青云,杨理,谢晴宜,吴友根,赵友兴.广藿香内生真菌Ogataea sp. RW-S10次级代谢产物研究[J].热带亚热带植物学报,2023,31(5):741~746

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History
  • Received:April 08,2022
  • Revised:July 01,2022
  • Adopted:July 21,2022
  • Online: September 26,2023
  • Published: September 20,2023
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