Saponins from Rhizomes of Panax zingiberensis

Abstract:

To investigate the chemical constituents from rhizomes of Panax zingiberensis, nine compounds were isolated and purified by methods of column chromatography on silica gel and Sephadex LH-20. Based on physical and chemical properties and spectral data,their structures were identified as ginsenoside SL₁ (1), ginsenoside Rh₁ (2), notoginsenoside R₈ (3), chikusetsusaponin IVa (4), vina-ginsenoside 10 (5), ginsenoside Rg₁ (6), spinasaponin A 28-O-β-d-glucopyranoside (7), oleanolic acid 28-O-β-d-glucopyranoside (8) and zingbroside R₁ (9). Compounds 1, 3, 5, 7, and 8 were isolated from P. zingiberensis for the first time. Compound 5 belongs to the ocotillol-type saponin, which was not previously reported from this species.