Abstract:Subgenus Ficus belongs to Moraceae, which is an important resource of fruit and herbal medicine. Ficus subgenus is widely planted in tropical and subtropical areas. It has outstanding economic value because of abundant bioactive compounds and multiple health benefits. Prenylated flavonoids are the characteristic bioactive compounds of Ficus subgenus, including 37 isoflavones, 2 flavanones, 7 flavones, and 1 chalcone. Numerous biological activities have been reported for these prenylated flavonoids, such as menopause relief, bone protection, anti-inflammation, anti-oxidation, cancer prevention and anti-bacteria activities. The updated information regarding the prenylated flavonoids in Ficus subgenus was summarized, and also their chemical structures and biological activities. The information is helpful for the development and utilization of this subgenus.
