JIA Yongxia
South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, ChinaYANG Qiuxia
South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, ChinaZENG Lei
Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou 510520, ChinaXU Qiaolin
Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou 510520, ChinaLIU Shaobo
College of Forestry and Landscape Architecture, South China Agricultural University, Guangzhou 510642, ChinaXU Xinlan
South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, ChinaTAN Jianwen
College of Forestry and Landscape Architecture, South China Agricultural University, Guangzhou 510642, ChinaTo study triterpenes from Akebia trifoliata and its antibacterial activities, nine triterpenes were isolated from the ethanol extract by various methods, such as silica gel, ODS, Sephadex LH-20 column chromatography and semi-preparative HPLC. Based on physical and chemical properties and spectral data, their structures were identified as stachlic acid A (1), oleanolic acid (2), ursolic acid (3), 2α,3β-dihydroxyolean-13(18)-en-28-oic acid (4), serratagenic acid (5), gypsogenic acid (6), 20α-hydroxyl-29-noroleanolic acid (7), mesembryanthemoidigenic acid (8) and 12α-hydroxy-δ-lactone (9). The compounds 2 and 3 had strong antibacterial activity against three tested bacterial strains in vitro. Compounds 1,4, 6 and 9 were isolated from A. trifoliata for the first time, compounds 3 and 7 were isolated from genus Akebia for the first time.
贾永霞,杨秋霞,曾雷,徐巧林,刘少博,徐信兰,谭建文.三叶木通藤茎的三萜成分及其抗菌活性研究[J].热带亚热带植物学报,2022,30(1):144~150
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