Abstract:Pleuropterus multiflorum, known as one of precious perennial Chinese traditional medicine, belonging to Pleuropterus genus and Polygonaceae family, distributed mainly in Sichuan, Yunnan, Guizhou and southern Shanxi and Gansu in China. The modern studies showed that P. multiflorum could be used for liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. In recent years, liver injuries caused by taking P. multiflorum have been reported worldwide. Therefore, the model of safety monitoring and risk management of P. multiflorum is very important. The chemical constituents and medicinal activities of P. multiflorum, including the toxic effects were summarized for the further studies and development, which is beneficial for the strengthening standardization of clinical applications, basic science research, quality control in manufacturing.
