Phenylpropanoids, Megastigmanes, Alkaloid, and Alkyl Glycosides from Isodon serra

Abstract:

To clarify the chemical constituents in the aerial parts of Isodon serra (Maxim.) Kudo, nine compounds were isolated from the ethanol extract. Basis on the spectral data, their structures were identified as methyl rosmarinate (1), 3,3'-bis(3,4-dihydro-4-hydroxy-6,8-dimethoxy-2H-1-benzopyran) (2), 7-megastigmene-3,5,6,9-tetrol (3), 7-megastigmene-3,5,6,9-tetrol 9-O-β-d-glucopyranoside (4), 5,6-epoxy-7-megastigmene-3,9-diol (5), (−)-loliolide (6), 3-formylindole (7), ethyl α-l-arabinofuranoside (8), and ethyl β-d-xylopyranoside (9). Compounds 1 and 2 belong to phenylpropanoids, 3-6 are megastigmanes, 7 is an alkaloid, 8 and 9 are alkyl glycosides. Compounds 2-9 were reported from this species for the first time.

Key words:Isodon serra;Phenylpropanoid;Megastigmane;Alkaloid;Alkyl glycoside