YIN Wei
Department of Pharmacology, Xinhua College of Anhui, Hefei 230088, ChinaYU Yang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, ChinaMA Qiu-li
Department of Pharmacology, Xinhua College of Anhui, Hefei 230088, ChinaCHEN Ting
Department of Pharmacology, Xinhua College of Anhui, Hefei 230088, ChinaZHANG Guo-sheng
Department of Pharmacology, Anhui University of Traditional Chinese Medicine, Hefei 230031, ChinaIn order to understand the chemical constituents of Osmanthus fragrans leaves, thirteen compounds were isolated from the 95% ethanol extract. On the basis of spectral data, their structures were identified as aromadendrin (1), genistein (2), lupinalbin A (3), methy oleanolate (4), 3-ketooleanolic acid (5), fouquierol (6), 19α-hydroxyl acetylursolic acid (7), betulin (8), stigmasta-3,5-dien-7-one (9), ciwujiatone (10), p-hydroxyaceto-phenone (11), entkaurane-3,16α-diol (12), and trigoflavidone A (13). All of compounds are isolated from the leaves of O. fragrans for the first time. The compounds 2, 3, 10 showed significant antitumor activities, and their activity determination to 4 kinds of tumor cells was reported for the first time.
尹伟,郁阳,马秋丽,陈婷,张国升.桂花叶的化学成分及抗肿瘤活性研究[J].热带亚热带植物学报,2018,26(2):178~184
Copy
