Triterpenoid Saponins from the Rhizome of Dioscorea spongiosa

Abstract:

In order to understand the chemical constituents of Dioscorea spongiosa, eight triterpenoid saponins were obtained from 70% EtOH extract of its rhizome. On the basis of their physicochemical and spectral data, these saponins were identified as 20(S)-ginsenoside Rh₁ (1), ginsenoside Rg₁ (2), ginsenoside Re (3), notoginsenoside R₁ (4), ginsenoside Rd (5), ginsenoside Rb₁ (6), hederagenin-3-O-α-L-arabinopyranoside (7), and akebiasaponin D (8). Among them, compounds 1, 2, 3, 5 and 6 were isolated from this species for the first time, and compounds 7 and 8 were obtained from the genus Dioscorea for the first time.