Home > Archive>Volume 24, Issue 4, 2016 >464-470. DOI:10.11926/j.issn.1005-3395.2016.04.015
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Screening and Isolation of Cytotoxicity in vitro from Invasive Plant Macfadyena unguis-cati L. (Bignoniaceae)
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College of Chemical Engineering,Huaqiao University;China;The Research and Development Center for Medicinal Plants and Plant Drugs,Xiamen Overseas Chinese Subtropical Plant Introduction Garden,Xiamen,;China,The Research and Development Center for Medicinal Plants and Plant Drugs,Xiamen Overseas Chinese Subtropical Plant Introduction Garden,Xiamen,The Research and Development Center for Medicinal Plants and Plant Drugs,Xiamen Overseas Chinese Subtropical Plant Introduction Garden,Xiamen,College of Chemical Engineering,Huaqiao University,The Research and Development Center for Medicinal Plants and Plant Drugs,Xiamen Overseas Chinese Subtropical Plant Introduction Garden,Xiamen,College of Chemical Engineering,Huaqiao University

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    Abstract:

    In order to screen and isolate the active constituents from invasive plant Macfadyena unguis-cati L. (Bignoniaceae), the anti-proliferative effects of SMMC7721, Bel7402 by different solvent extraction fractions of ethanol extracts of M. unguis-cati in vitro were studied by using MTT assay. The results showed that the chloroform fraction of ethanol extracts had strong inhibitory effect on liver cancer cells, and then was petroleum ether fraction. An active constituent isolated from chloroform fraction, ursolic acid, had strong inhibitory effect. Therefore, invasive plant M. unguis-cati L. has cytotoxicity in vitro, and one of the main active components is ursolic acid.

    Reference
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郑志忠,谌迪,刘韶松,邓远,林志灿,明艳林.入侵植物猫爪藤体外细胞毒活性成分的筛选分离[J].热带亚热带植物学报,2016,24(4):464~470

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History
  • Received:October 10,2015
  • Revised:January 06,2016
  • Adopted:March 24,2016
  • Online: July 15,2016
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