Abstract:In order to find the bioactive components from the stems of Chukrasia tabularis, ten compounds were isolated from its EtOH extract by using chromatographic techniques. On the basis of spectral data, their structures were identified as 3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-one (1), 6-hydroxy-1,3,5,7-tetrameth-oxy-9H-xanthen-9-one (2), 2,6,2',6'-tetramethoxy-4,4'-bis(2,3-epoxy-1-hydroxypropyl) biphenyl (3), cleomiscosin D (4), chuktabularin A (5), chuktabularin B (6), chubularisin H (7), chubularisin I (8), tabularisin A (9), and tabularisin B (10). Compounds 1-4 were isolated from the genus Chukrasia for the first time. Furthermore, compounds 1, 2, 6, 7 and 9 exhibited inhibitory activity against α-glucosidase in vitro.
