Chemical Constituents from Rwandan Plant Rosmarinus officinalis L. (I)

Abstract:

In order to understand the chemical constituents of Rosmarinus officinalis, 13 compounds were isolated from its 95% EtOH extract. On the basis of spectral data, their structures were identified as (Z)-3- hexenyl glucoside (1), (Z)-3-hexenyl O-β-D-glucopyranosyl-(1''→6')-β-D-glucopyranoside (2), erythritol-1-O- (6-O-trans-caffeoyl)-β-D-glucopyranoside (3), 2,3,4,5-tetrahydroxyhexyl-6-O-trans-caffeoyl-β-glucopyranoside (4), 1,2,3,4-tetrahydroxy-2-methylbutane-4-O-(6-O-trans-caffeoyl)-β-D-glucopyranoside (5), caffeic acid (6), rosmarinic acid (7), methyl rosmarinate (8), methyl benzoate-4-β-glucoside (9), benzyl-β-D-glucopyranoside (10), benzyl-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside (11), 1,2-di-O-β-D-glucopranosyl-4-allylbenzene (12) and (+)-syringaresinol-4'-O-β-D-glucopyranoside (13). Among them, compounds 1-5 and 8-13 were isolated from the Rosmarinus genus for the first time. For the known ones, the NMR data of compound 13 was corrected.