Flavonoids from the Leaves of Myoporum bontioides
Author:
Affiliation:

South China Agricultural University,South China Agricultural University,South China Agricultural University,Institute of Biomaterial, College of Science, South China Agricultural University

  • Article
  • | |
  • Metrics
  • |
  • Reference [18]
  • |
  • Related [20]
  • |
  • Cited by [0]
  • | |
  • Comments
    Abstract:

    In order to understand the chemical constituents extracted from Myoporum bontioides A. Gray, eleven flavonoid compounds were isolated from the leaves of M. bontioides by chromatographic separation methods. On the basis of spectral data, they were identified as tangeretin (1), sinensetin (2), 5,4'-dihydroxy-6,7,8,3'-tetramethoxyflavone (3), 4',5,7,8-pentamethoxyflavone (4), 5-demethylnobiletin (5), 5-hydroxy- 6,7,3',4'-tetramethoxyflavone (6), nobiletin (7), dihydrokaempferol (8), luteolin (9), 3-methoxy-3',4',5,7- tetrahydroxyflavone (10), and apigenin (11). All these compounds were obtained from M. bontioides for the first time except compound 9. The compounds 1, 2, 8 and 9 had strong antifungal activity against Colletotrichum musae by using spore germination inhibition assay. So, these could provide a theoretical basis for utilizing the active ingredients in leaves of M. bontioides.

    Reference
    [1] Bashari A A, Zhong G H, Hu M Y. Effects on the bioactivity of the extracts from Myoporum bontioides against imported cabbage worm (Pieris rapae) [J]. J S China Agri Univ (Nat Sci), 1999, 20(3): 28-31. Bashari A A, 钟国华, 胡美英. 苦槛蓝抽提物对菜青虫生物活 性的影响 [J]. 华南农业大学学报: 自然科学版, 1999, 20(3):28-31.
    [2] Deng Y C, Yang Z, Yu Y Z, et al. Inhibitory activity against plant pathogenic fungi of extracts from Myoporum bontioides A. Gray and indentification of active ingredients [J]. Pest Manag Sci, 2008, 64(2): 203-207.
    [3] Li X Z, Li C Y, Wu L X, et al. Chemical constituents from leaves of Myoporum bontioides [J]. Chin Trad Herb Drug, 2011, 42(11): 2204-2207. 李显珍, 李春远, 吴伦秀, 等. 苦槛蓝叶化学成分研究 [J]. 中草 药, 2011, 42(11): 2204-2207.
    [4] He Y B, Gu W X, Pang X F. Bioactivity of several flavonoids against Plutella xylostella (L.) [J]. Chin J Trop Agri, 2003, 23(6): 19-25,63. 何衍彪, 谷文祥, 庞雄飞. 飞机草和苦槛蓝中的黄酮类提取物对 小菜蛾的生物活性 [J]. 热带农业科学, 2003, 23(6): 19-25,63.
    [5] Nagase H, Omae N, Omori A, et al. Nobiletin and its related flavonoids with CRE-dependent transcription stimulating and neuritegenic activities [J]. Biochem Biophys Res Commun, 2005, 337(4): 1330-1336.
    [6] Hamdan D, El-Readi M Z, Tahrani A, et al. Chemical composition and biological activity of Citrus jambhiri Lush [J]. Food Chem, 2011, 127(2): 394-403.
    [7] Machida K, Osawa K. On the flavonoid constituents from the peels of Citrus hassaku Hort. ex Tanaka [J]. Chem Pharm Bull, 1989, 37(4): 1092-1094.
    [8] Song F J, Gao J, Yang G Z, et al. Studies on the chemical constituents of Rabdosia rubescens Hemsl. in the western part of Hubei Province [J]. Lishizhen Med Mat Med Res, 2011, 22(5): 1069-1070. 宋发军, 高洁, 杨光忠, 等. 鄂西冬凌草化学成分研究 [J]. 时珍 国医国药, 2011, 22(5): 1069-1070.
    [9] Wu W, Wang C Z, Li X, et al. Chemical constituents of antitumor active fraction of Lysimachia clethroides [J]. Chin Trad Herb Drug, 2011, 42(1): 38-41. 吴威, 王春枝, 李夏, 等. 珍珠菜抗肿瘤有效部位化学成分研究[J]. 中草药, 2011, 42(1): 38-41.
    [10] Yang Y, Wang Y F, Zhao L, et al. Chemical constituents of Inula cappa flowers [J]. Chin Trad Herb Drug, 2011, 42(6): 1083- 1086. 杨雁, 王于方, 赵雷, 等. 羊耳菊花的化学成分研究 [J]. 中草药, 2011, 42(6): 1083-1086.
    [11] van Puyvelde L, de Kimpe N, Costa J, et al. Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin [J]. J Nat Prod, 1989, 52(3): 629-633.
    [12] Zhang J, Zheng Y N, Han L K. Studies on chemical constituents of leaves of Salix matsudana Koidz and their influence on lipolysis [J]. China J Chin Mat Med, 2000, 25(9): 538-541. 张晶, 郑毅男, 韩立坤. 旱柳叶的化学成分及其药理活性的研 究 [J]. 中国中药杂志, 2000, 25(9): 538-541.
    [13] Qiu N S. Controlling effect of the tank mixture of fosethylalnminum and isoprothiolane on rice blast disease [J]. Subtrop Agri Res, 2008, 4(1): 29-32. 丘能升. 稻瘟灵与三乙膦酸铝混剂对稻瘟病的防治效果 [J]. 亚热带农业研究, 2008, 4(1): 29-32.
    [14] Jia C S. Calculatiang the LC50 of insecticides with software SPSS [J]. Chin Bull Entomol, 2006, 43(3): 414-417. 贾春生. 利用SPSS软件计算杀虫剂的LC50 [J]. 昆虫知识, 2006, 43(3): 414-417.
    [15] Yang Y N. Study of the polymethoxylated flavonoids in Fructus Aurantii immaturus [D]. Jilin: Jilin University, 2007: 1-102. 杨桠楠. 枳实中多甲氧基黄酮类化学成分的研究 [D]. 吉林: 吉 林大学, 2007: 1-102.
    [16] Kawall S, Tomono Y, Katase E, et al. Antiproliferative activity of flavonoids on several cancer cell lines [J]. Biosci Biotechn Biochem, 1999, 63(5): 896-899.
    [17] Dong Y, Ji G, Cao A L, et al. Effects of sinensetin on proliferation and apoptosis of human gastric cancer AGS cells [J]. China J Chin Mat Med, 2011, 36(6): 790-794. 董杨, 季光, 曹爱丽, 等. 甜橙黄酮对人胃癌AGS细胞增殖和 凋亡的作用及其机制研究 [J]. 中国中药杂志, 2011, 36(6): 790-794.
    [18] Wang X W, Mao Y, Fan M, et al. Isolation, identification and activity determination on the anti-hypoxic components of Hypericum japonicum Thunb. [J]. J Shenyang Pharm Univ, 2009, 26(9): 701-708. 王晓炜, 毛羽, 范明, 等. 田基黄抗缺氧活性成分的分离鉴定与 活性测定 [J]. 沈阳药科大学学报, 2009, 26(9): 701-708.
    Comments
    Comments
    分享到微博
    Submit
Get Citation

戴航,黄立兰,郭育晖,谷文祥.苦槛蓝叶中的黄酮类化合物[J].热带亚热带植物学报,2013,21(3):266~272

Copy
Share
Article Metrics
  • Abstract:2691
  • PDF: 2604
  • HTML: 0
  • Cited by: 0
History
  • Received:October 09,2012
  • Revised:December 28,2012
  • Adopted:January 22,2013
  • Online: May 22,2013
Article QR Code