The pathogenesis-related protein encoding genes were cloned from sugarcane (Saccharum officenarum) leaves, named as SoSOD、SoCHIT、SoPOD and SoTPS6P. Their expression in S. officenarum leaves infected by Gibberella fujikuroi was studied by real-time quantitative RT-PCR. The results showed that the expression of SoSOD、SoCHIT、SoPOD and SoTPS6P genes could be induced in chewing cane leaves after and the expression levels in leaves of different chewing cane cultivars were different. The expression levels of these genes in cultivars ‘Fengchengzipi’, ‘Baishang’, ‘Fuan’and ‘adila’leaves were higher than those in cultivars ‘Wenlin’, ‘Ninde’and ‘Waigandan’. These indicated that the expression levels of SoSOD、SoCHIT、SoPOD and SoTPS6P associated with the resistance of different chewing cane cultivars to G. fujikuroi.