Abstract:The chemical structures and pharmacology of triterpenoid compounds in the genus Lysimachia L. are reviewed. Triterpenoid saponins in this genus, characterized by the oleanane-derived sapogenols, can be classified into two primary types of 13β, 28-oxide (Ⅰ) and Δ12-17-CH2OH (Ⅱ). The chemical transformations of the sapogenols in typesⅠ and Ⅱ are also described.