走马胎中大叶紫金牛酚的分离鉴定与生物活性评价

Isolation, Identification and Biological Evaluation of Gigantifolinol from Ardisia gigantifolia

摘要:

为了解走马胎（Ardisia gigantifolia）的化学成分，从其乙酸乙酯提取物中分离鉴定出大叶紫金牛酚。体外活性评价结果表明，大叶紫金牛酚具有良好的抗炎、抗肿瘤活性以及一定的神经保护作用。这是首次对大叶紫金牛酚进行系统研究，为综合开发与利用走马胎提供科学依据。

Abstract:

In order to understand the chemical constituents of Ardisia gigantifolia, the gigantifolinol were isolated and identified from EtOAc extract. In vitro activity screening, gigantifolinol showed potent anti-inflammatory and anti-tumor activities, and moderate neuroprotection activities. This is the first systematic study of gigantifolinol, which might provide a scientific basis to the development and utilization of A. gigantifolia.