首页 | 本刊简介 | 编委会 | 投稿征稿 | 期刊订阅 | 下载中心 | English
 
   
  论文快速检索

请输入关键词

 

 

   
  信息公告
访问总次数
16056340
今日访问
107
当前在线
0人
 
引用本文:
【打印本页】   【HTML】   【下载PDF全文】   查看/发表评论  【EndNote】   【RefMan】   【BibTex】
←前一篇|后一篇→ 过刊浏览    高级检索
本文已被:浏览 1434次   下载 39 本文二维码信息
码上扫一扫!
分享到: 微信 更多
何首乌化学成分及其药理活性的研究进展
沈晓静1,2, 张敢娟1, 吕奇1, 杨俊滔1, 王青1, 姜薇薇1
1.云南农业大学理学院, 昆明 650201;2.云南省天然药物药理重点实验, 昆明医科大学, 昆明 650500
摘要:  何首乌(Pleuropterus multiflorus)是一种珍贵的多年生中药,为蓼科(Polygonaceae)何首乌属植物,主要分布在四川、云南、贵州以及山西和甘肃南部,可用于治疗肝损伤、癌症、糖尿病、脱发、动脉粥样硬化以及神经退行性疾病。近年来,国际上有报道称摄入何首乌会引起肝损伤,因此,建立何首乌的安全监测和风险管理模型对何首乌的开发利用具有重要意义。对何首乌的化学成分、药理活性及其毒副作用进行了综述,为何首乌的临床应用、科学研究和生产质量控制提供参考。
关键词:  何首乌  化学成分  药理活性  综述
DOI:10.11926/jtsb.4304
分类号:
基金项目:This work was supported by the Project for Scientific Research of Yunnan Education Department (Grant No. 2020J0241), the Joint Project for Agricultural Basic Research in Yunnan Province (Grant No. 2018FG001-037), and the Open Projects of Yunnan Key Laboratory of Pharmacology for Natural Products (Grant No. 70120030506).
Advances in Chemical Constituents and Pharmacological Activities of Pleuropterus multiflorus
Shen Xiao-jing1,2, Zhang Gan-juan1, Lü Qi1, Yang Jun-tao1, Wang Qing1, Jiang Wei-wei1
1.College of Science, Yunnan Agricultural University, Kunming 65020, China;2.Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, China
Abstract:  Pleuropterus multiflorum, known as one of precious perennial Chinese traditional medicine, belonging to Pleuropterus genus and Polygonaceae family, distributed mainly in Sichuan, Yunnan, Guizhou and southern Shanxi and Gansu in China. The modern studies showed that P. multiflorum could be used for liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. In recent years, liver injuries caused by taking P. multiflorum have been reported worldwide. Therefore, the model of safety monitoring and risk management of P. multiflorum is very important. The chemical constituents and medicinal activities of P. multiflorum, including the toxic effects were summarized for the further studies and development, which is beneficial for the strengthening standardization of clinical applications, basic science research, quality control in manufacturing.
Key words:  Pleuropterus multiflorum  Chemical constituent  Pharmacological activities  Review

Copyright 2007 版权所有 中国科学院华南植物园《热带亚热带植物学报》编辑部
地址: 广州市天河区兴科路723号 中国科学院华南植物园 《热带亚热带植物学报》编辑部 邮编:510650 电话: 86 (0)20-3725 2514  传真: E-mail: jtsb@scib.ac.cn
本系统由北京勤云科技发展有限公司设计
京ICP备09084417号-2