Abstract:Polygonatum kingianum, as one of the important traditional Chinese medicinal materials in Yunnan, has seen a decline in its wild resources due to over-harvesting, and the research on its artificial cultivation is relatively insufficient, which has seriously affected the protection and utilization of its resources. Therefore, predicting the spatial changes of its potential suitable habitat is of great significance. The potential suitable habitat of P. kingianum in China was predicted by using Maxent model and geographic information system, combined with 63 valid distribution records in China and 15 environmental variables. The results showed that the area under the receiver operating characteristic curve was 0.971, indicating that the model had good predictive ability; the suitable habitat of P. kingianum was mainly concentrated in the southwest region of China, including Yunnan, Guizhou, Guangxi, Sichuan and Chongqing; annual precipitation, precipitation in the driest quarter, altitude and the lowest temperature in the coldest month played a key role in the geographical distribution of P. kingianum; in the future, the center of the suitable habitat of P. kingianum will gradually shift towards Guizhou. This would be provided a theoretical basis for the in-situ and ex-situ conservation of P. kingianum and the selection of artificial high-efficiency and high-quality cultivation bases, and has important practical significance for the protection and utilization of its germplasm resources.