首页 > 过刊浏览>2023年第31卷第1期 >141-146. DOI:10.11926/jtsb.4539
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大叶桃花心木树皮化学成分研究
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安徽省自然科学基金项目（2008085MH289）；安徽省高校优秀青年人才支持计划重点项目（gxyqZD2019035）资助


Chemical Constituents from Barks of Swietenia macrophylla
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    摘要:

    为了解大叶桃花心木（Swietenia macrophylla）树皮的化学成分，采用硅胶、凝胶、制备液相等手段分离、纯化，从其树皮提取物中分离得到9个化合物。根据理化性质及波谱数据，鉴定化合物结构分别为香草酸（1）、东莨菪素（2）、大黄素甲醚（3）、3，4，5-三甲氧基苯基-β-d-吡喃葡萄糖苷（4）、（+）-儿茶素（5）、5′-甲氧基异落叶松脂素-9′-O-β-d-吡喃木糖苷（6）、南烛木树脂酚-9′-O-β-d-吡喃木糖苷（7）、豆甾醇（8）、豆甾醇-3-O-β-d-吡喃葡萄糖苷（9）。除化合物5外，其余化合物为首次从该植物中分离。细胞毒活性试验表明化合物均无显著的细胞毒活性。

    Abstract:

    To understand the chemical constituents of Swietenia macrophylla barks, nine compounds were isolated and purified from bark extracts by using silica gel, gel and MPLC. Based on the physicochemical properties and spectral data, their structures were identified as vanillic acid (1), scopoletin (2), physcion (3), 3,4,5-trimeth-oxyphenyl-β-d-glucopyranoside (4), (+)-catechin (5), (+)-5'-methoxy-isolariciresinol-9'-O-β-dxylopyranoside (6), lyoniresinol-9'-O-β-d-xylopyranoside (7), stigmasterol (8), stigmasterol-3-O-β-d-glucopyranoside (9). Except for compound 5, the remaining compounds were isolated from this plant for the first time. The cytotoxicity assay showed that none of the compounds had significant cytotoxic activities.

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张曼莉,孙云鹏,金文芳,黄宇飞,徐泽荣,刘劲松,王国凯.大叶桃花心木树皮化学成分研究[J].热带亚热带植物学报,2023,31(1):141~146

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  • 收稿日期:2021-09-30
  • 最后修改日期:2022-03-22
  • 在线发布日期: 2023-02-24
  • 出版日期: 2023-01-20
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