首页 > 过刊浏览>2021年第29卷第1期 >105-111. DOI:10.11926/jtsb.4246
PDF HTML阅读 XML下载 导出引用 引用提醒
杨桃叶的化学成分研究
作者:
基金项目:

国家重点基础研究发展计划（973计划）（2013CB127106）；广东省应用型科技研发专项（2016B020239004）资助


Chemical Constituents from the Leaves of Averrhoa carambola
Author:
  • YANG Yue

    YANG Yue

    Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China;University of Chinese Academy of Sciences, Beijing 100049, China
    在期刊界中查找
    在百度中查找
    在本站中查找
  • XIE Hai-hui

    XIE Hai-hui

    Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China;University of Chinese Academy of Sciences, Beijing 100049, China
    在期刊界中查找
    在百度中查找
    在本站中查找
  • 摘要
    • | |
  • 访问统计
    • |
  • 参考文献 [28]
    • |
  • 相似文献 [20]
    • | | |
  • 文章评论
    摘要:

    为阐明酢浆草科植物杨桃（Averrhoa carambola）的化学成分，运用有机溶剂提取、萃取及多种色谱分离技术，从其叶中分离得到11个化合物。经光波谱分析，分别鉴定为苯基β-d-葡萄糖苷（1）、3，4，5-三甲氧基苯基β-d-葡萄糖苷（2）、苄基β-d-葡萄糖苷（3）、2-苯乙基芸香糖苷（4）、1-O-（3，5-二甲氧基-4-羟基苯甲酰）-β-d-葡萄糖（5）、5-羟基麦芽酚（6）、麦芽酚苷（7）、麦芽酚3-O-[6-O-（3-羟基-3-甲基-5-丁基戊二酰）]-β-d-葡萄糖苷（8）、乙基β-d-呋喃果糖苷（9）、丁基β-d-呋喃果糖苷（10）和鲨烯（11）。化合物8是1个新的人工产物，除化合物2和3外均为首次从杨桃属植物中得到。部分化合物与杨桃叶的抗炎、抗氧化和抗肿瘤作用相关。

    Abstract:

    To clarify the chemical constituents in the leaves of Averrhoa carambola (Oxalidaceae), eleven compounds were isolated by means of organic solvent extraction and fractionation as well as diverse chromato-graphic separation techniques. On the basis of spectroscopic data, their structures were identified as phenyl β-d-glucoside (1), 3,4,5-trimethoxyphenyl β-d-glucoside (2), benzyl β-d-glucoside (3), 2-phenethyl rutinoside (4), 1-O-(3,5-dimethoxy-4-hydroxybenzoyl)-β-d-glucose (5), 5-hydroxymaltol (6), maltol β-d-glucoside (7), maltol 3-O-[6-O-(3-hydroxy-3-methyl-5-butylglutaroyl)]-β-d-glucoside (8), ethyl β-d-fructofuranoside (9), butyl β-d-fructofuranoside (10), and squalene (11), respectively. Compound 8 was a new artifact, and the others excluding 2 and 3 were obtained from the genus Averrhoa for the first time. Some compounds were related to the anti-inflammatory, antioxidant, and anti-tumor effects of the leaves.

    参考文献
    [1] LIU Q R. Florae Republicae Popularis Sinicae, Tomus 43(1)[M]. Beijing:Science Press, 1998:4-6. 刘全儒. 中国植物志, 第43卷第1分册[M]. 北京:科学出版社, 1998:4-6.
    [2] State Administration of Traditional Chinese Medicine. Chinese Materia Medica, Tomus 12[M]. Shanghai:Shanghai Scientific & Technical Publishers, 1999:713-715. 国家中医药管理局. 中华本草, 第12卷[M]. 上海:上海科学技术出版社, 1999:713-715.
    [3] ALADAILEH S H, SAGHIR S A M, MURUGESU K, et al. Antihyper-lipidemic and antioxidant effects of Averrhoa carambola extract in high-fat diet-fed rats[J]. Biomedicines, 2019, 7(3):72. doi:10.3390/biomedicines7030072.
    [4] LIU F Z, SONG X M, WANG X L, et al. Hypoglycemic effect of total flavones from carambola leaf[J]. Chin J Exp Tradit Med Form, 2013, 19(11):279-281. doi:10.11653/syfj2013110279. 刘方洲, 宋献美, 王晓丽, 等. 杨桃叶总黄酮的降血糖作用[J]. 中国实验方剂学杂志, 2013, 19(11):279-281. doi:10.11653/syfj2013110279.
    [5] SONCINI R, SANTIAGO M B, ORLAND L, et al. Hypotensive effect of aqueous extract of Averrhoa carambola L. (Oxalidaceae) in rats:An in vivo and in vitro approach[J]. J Ethnopharmacol, 2011, 133(2):353-357. doi:10.1016/j.jep.2010.10.001.
    [6] CABRINI D A, MORESCO H H, IMAZU P, et al. Analysis of the potential topical anti-inflammatory activity of Averrhoa carambola L. in mice[J]. Evid Based Complement Alternat Med, 2011, 2011:908059. doi:10.1093/ecam/neq026.
    [7] CAZAROLL L H, KAPPEL V D, PEREIRA D F, et al. Anti-hyper-glycemic action of apigenin-6-C-β-fucopyranoside from Averrhoa carambola[J]. Fitoterapia, 2012, 83(7):1176-1183. doi:10.1016/j. fitote.2012.07.003.
    [8] MORESCO H H, QUEIROZ G S, PIZZOLATTI M G, et al. Chemical constituents and evaluation of the toxic and antioxidant activities of Averrhoa carambola leaves[J]. Rev Bras Farmacogn, 2012, 22(2):319-324. doi:10.1590/S0102-695X2011005000217.
    [9] ARAHO D, MIYAKOSHI M, CHOU W H, et al. A new flavone C-glycoside from the leaves of Averrhoa carambola[J]. Nat Med, 2005, 59(3):113-116. doi:10.1016/j.apsusc.2004.03.089.
    [10] YANG Y, XIE H H, JIANG Y M, et al. Flavan-3-ols and 2-diglycosyloxybenzoates from the leaves of Averrhoa carambola[J]. Fitoterapia, 2020, 140:104442. doi:10.1016/j.fitote.2019.104442.
    [11] YANG Y, JIA X C, XIE H H, et al. Dihydrochalcone C-glycosides from Averrhoa carambola leaves[J]. Phytochemistry, 2020, 174:112364. doi:10.1016/j.phytochem.2020.112364.
    [12] PU X Y, GAO L B, WANG W, et al. Chemical constituents from Hemiphragma heterophyllum and their α-glucosidase inhibitory activities[J]. J Yunnan Minzu Univ (Nat Sci), 2019, 28(5):423-427. 普晓云, 高利斌, 王韦, 等. 鞭打绣球的化学成分及其α-葡萄糖苷酶抑制活性的研究[J]. 云南民族大学学报(自然科学版), 2019, 28(5):423-427.
    [13] ACHENBACH H, BENIRSCHKE G. Joannesialactone and other compounds from Joannesia princeps[J]. Phytochemistry, 1997, 45(1):149-157. doi:10.1016/s0031-9422(96)00777-7.
    [14] YANG D, XIE H H. Aromatics and flavonoids from strawberry cv. Falandi[J]. J Trop Subtrop Bot, 2017, 25(6):617-624. doi:10.11926/jtsb.3758. 杨丹, 谢海辉. 法兰地草莓的芳香类和黄酮类成分[J]. 热带亚热带植物学报, 2017, 25(6):617-624. doi:10.11926/jtsb.3758.
    [15] JIA X C, YANG D, XIE H H. Chemical constituents from fresh sweet star fruit[J]. J Trop Subtrop Bot, 2017, 25(3):309-314. doi:10.11926/jtsb.3709. 贾栩超, 杨丹, 谢海辉. 甜杨桃鲜果的化学成分研究[J]. 热带亚热带植物学报, 2017, 25(3):309-314. doi:10.11926/jtsb.3709.
    [16] ZHANG W D, CHEN W S, KONG D Y, et al. Studies on the chemical constituents of Erigeron breviscapus[J]. Chin Pharm J, 2000, 35(8):10-12. 张卫东, 陈万生, 孔德云, 等. 灯盏细辛化学成分的研究[J]. 中国药学杂志, 2000, 35(8):10-12.
    [17] PU S C, GUO Y Q, GAO W Y. Studies on the chemical constituents of Hydrocotyle sibthorpioides[J]. Chin Trad Herb Drugs, 2010, 41(9):1440-1442. 蒲首丞, 郭远强, 高文元. 天胡荽化学成分的研究[J]. 中草药, 2010, 41(9):1440-1442.
    [18] CHU H B, HE W J, ZHANG Y M, et al. Flavonoids and nor-sesquiterpenes of Pedicularis densispica[J]. China J Chin Mat Med, 2011, 36(19):2672-2675. doi:10.4268/cjcmm20111914. 褚洪标, 贺文军, 张玉梅, 等. 密穗马先蒿中黄酮和降倍半萜成分[J]. 中国中药杂志, 2011, 36(19):2672-2675. doi:10.4268/cjcmm20111914.
    [19] LI W, ASADA Y, YOSHIKAWA T. Flavonoid constituents from Glycyrrhiza glabra hairy root cultures[J]. Phytochemistry, 2000, 55(5):447-456. doi:10.1016/S0031-9422(00)00337-X.
    [20] XIANG M X, HE Y J, HE F, et al. Chemical composition of n-butanol fraction from Polygonum amplexicaule var. sinense[J]. J Chin Med Mat, 2015, 38(9):1872-1874. doi:10.13863/j.issn1001-4454.2015.09.018. 向梅先, 胡亚京, 何峰, 等. 血三七正丁醇部位化学成分研究[J]. 中药材, 2015, 38(9):1872-1874. doi:10.13863/j.issn1001-4454.2015.09.018.
    [21] SUN G T, HU X J. Chemical constituents in Capparis masaikai Lévl Kernels[J]. J Kunming Univ Sci Technol (Nat Sci), 2017, 42(5):85-89. doi:10.16112/j.cnki.53-1223/n.2017.05.013. 孙国太, 胡旭佳. 马槟榔种仁的化学成分研究[J]. 昆明理工大学学报(自然科学版), 2017, 42(5):85-89. doi:10.16112/j.cnki.53-1223/n.2017.05.013.
    [22] YANG M H, YANG X Q, ZHANG F M, et al. Chemical constituents from Woodwardia unigemmate[J]. Chin Trad Herb Drugs, 2009, 40(10):1546-1549. 杨明慧, 杨雪琼, 张凤梅, 等. 单芽狗脊蕨的化学成分[J]. 中草药, 2009, 40(10):1546-1549.
    [23] ZHOU X L, QIN C H, MEI Y, et al. Chemical constituents in leaf of Rhododendron anthopogon[J]. Chin Trad Herb Drugs, 2010, 41(2):206-208. 周先礼, 秦长红, 梅莹, 等. 髯花杜鹃叶的化学成分研究[J]. 中草药, 2010, 41(2):206-208.
    [24] NI L, HUANG W, SHI Y, et al. Chemical constituents from the bark of Bauhinia purpurea and their NO inhibitory activities[J]. Nat Prod Res, 2018, 23:1-6. doi:10.1080/14786419.2018.1543672.
    [25] KUMBOONMA P, SAENGLEE S, SENAWONG T, et al. Histone deacetylase inhibitors and antioxidants from the root of Gluta usitata[J]. Nat Prod Commun, 2019, 14(12):1-7. doi:10.1177/1934578X19895370.
    [26] van THANH N, THAO N P, DAT L D, et al. Two new naphthalene glucosides and other bioactive compounds from the carnivorous plant Nepenthes mirabilis[J]. Arch Pharm Res, 2015, 38(10):1774-1782. doi:10.1007/s12272-015-0576-9.
    [27] PU S C. Study on anti-tumor constituents from Hydrocotyle sibthor-pioides[J]. J Anhui Agric Sci, 2014, 42(11):3238-3239. doi:10.13989/j.cnki.0517-6611.2014.11.098. 蒲首丞. 天胡荽抗肿瘤活性成分研究[J]. 安徽农业科学, 2014, 42(11):3238-3239. doi:10.13989/j.cnki.0517-6611.2014.11.098.
    [28] BALWANI S, NANDI D, JAISANKAR P, et al. 2-Methyl-pyran-4-one-3-O-β-d-glucopyranoside isolated from leaves of Punica granatum inhibits the TNFα-induced cell adhesion molecules expression by blocking nuclear transcription factor-κB (NF-κB)[J]. Biochimie, 2011, 93(5):921-930. doi:10.1016/j.biochi.2011.01.010.
    引证文献
    网友评论
    网友评论
    分享到微博
    发 布
引用本文

杨月,谢海辉.杨桃叶的化学成分研究[J].热带亚热带植物学报,2021,29(1):105~111

复制
分享
文章指标
  • 点击次数:546
  • 下载次数: 724
  • HTML阅读次数: 541
  • 引用次数: 0
历史
  • 收稿日期:2020-05-13
  • 最后修改日期:2020-06-11
  • 在线发布日期: 2021-01-19
文章二维码
您是第16721984 位访问者
主管单位：中国科学院
主办单位：中国科学院华南植物园 广东省植物学会
地址：广州市天河区兴科路723号 中国科学院华南植物园 《热带亚热带植物学报》编辑部
电话：86 (0)20-3725 2514
热带亚热带植物学报 ® 2025 版权所有