阔叶丰花草的三萜酸类化学成分研究

Triterpenic Acids from Spermacoce latifolia

摘要:

为了解阔叶丰花草(Spermacoce latifolia)的化学成分, 从其全株乙醇提取物中分离得到7个三萜类化合物, 经过波谱分析, 他们的结构鉴定为:熊果酸 (1)、mesembryanthemoidigenic acid (2)、3β,6β-dihydroxy-olean-12-ene-28-oic acid (3)、scutellaricacid (4)、arjunic acid (5)、29-hydroxyhederagenin (6)和3β,6β,23-trihydroxy-olean-12-en-28-oic acid (7)。抗菌活性测试结果表明化合物1、3、4 和7 对部分测试菌株具有显著的抑制作用。

Abstract:

In order to understand the chemical constituents of Spermacoce latifolia, seven compounds were isolated from its whole plant. On the basis of spectral data, they were identified as ursolic acid (1), mesembryanthemoidigenic acid (2), 3β,6β-dihydroxy-olean-12-ene-28-oic acid (3), scutellaric acid (4), arjunic acid (5), 29-hydroxyhederagenin (6) and 3β,6β,23-trihydroxy-olean-12-en-28-oic acid (7). Compounds 1, 3, 4 and 7 showed significant inhibitory activity toward parts of the assayed bacterial strains.