鸡血藤中的酚酸类化合物

Phenolic Constituents from the Stems of Spatholobus suberectus Dunn

摘要:

为了解鸡血藤（Spatholobus suberectus Dunn）的化学成分，从鸡血藤的95% 乙醇提取物中分离出15 个酚酸类单体成分，经波谱学分析分别鉴定为：没食子酸（1）、tachioside（2）、isotachioside（3）、canthoside D（4）、3，5-二甲氧基-4-羟基苯基-1-O-β-D-吡喃葡萄糖苷（5）、2，6-二甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷（6）、4-羟甲基-2，6-二甲氧基苯基-β-D-吡喃葡萄糖苷（7）、丁香酸葡萄糖苷（8）、3-甲氧基苯乙醇-4-O-β-D-葡吡喃糖苷（9）、2-（4-hydroxy-3，5-dimethoxyphenyl）ethyl-β-D-glucopyranoside（10）、4，6-二羟基-2-O-（β-D-吡喃葡萄糖苷）苯乙酮（11）、松香（12）、顺式紫丁香苷（13）、（-）-（7R，8S）-guaiacylglycerol 8-O-β-Dglucopyranoside（14）和l-threo-guaiacylglycerol-8-O-β-glucopyranoside（15）。其中，化合物2 ~ 8 和10 ~ 15 为首次从密花豆属植物中分离得到。

Abstract:

In order to understand the chemical constituents of Spatholobus suberectus Dunn, 15 phenolic constituents were obtained from 95% EtOH extract of S. suberectus stems by chromatographic separation methods. On the basis of spectral data, they were identified as gallic acid (1), tachioside (2), isotachioside (3), canthoside D (4), koaburaside (5), 2,6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (6), 4-hydroxymethyl-2,6- dimethoxyphenyl-β-D-glucopyranoside (7), glucosyringic acid (8), 3-methoxyphenethyl alcohol-4-O-β-Dglucopyranoside (9), 2-(4-hydroxy-3,5-dimethoxyphenyl)ethyl-β-D-glucopyranoside (10), 4,6-dihydroxy-2-O- (β-D-glucopyranosyl)-acetophenone (11), rosin (12), cis-syringin (13), (-)-(7R,8S)-guaiacylglycerol 8-O-β-Dglucopyranoside (14), and l-threo-guaiacylglycerol-8-O-β-glucopyranoside (15). Among them, compounds 2 - 8 and 10 - 15 were isolated from the Spatholobus genus at first time.