一株茄病镰刀菌的代谢产物研究

Metabolits of Fusarium solani

摘要:

一株茄病镰刀菌(Fusarium solani)固体发酵培养物经柱层析分离得到10个化合物。通过波谱分析, 分别鉴定为对羟基苯甲酸甲酯 (1)、水杨酸甲酯 (2)、水杨酸戊酯 (3)、香草乙酮 (4)、草夹竹桃苷 (5)、2-甲氧基-4-乙烯苯基-β-D-吡喃葡萄糖苷 (6)、1-O-β-D-glucopyranosyl-(2S,3R,8E)-2-[(2R)-2-hydroxylpal-mitoylamino]-8-octadecene-1,3-diol (7)、1-O-β-D-glucopyranosyl-(2S,3R,4E,8E)-2-[(2R)-2-hydroxyhex-adecanoylaino]-8-octadecene-1,3-diol (8)、脑苷脂D (9)和脑苷脂C (10)。所有化合物均为首次从茄病镰刀菌中分离得到, 其中化合物6首次作为天然产物报道。

Abstract:

Ten compounds were isolated from the culture of Fusarium solani. On the basis of spectral data, they were identified as methylparaben (1), methyl salicylate (2), amyl salicylate (3), acetovanillone (4), androsin (5), 2-methoxy-4-vinylphenyl-β-D-glucopyranoside (6), 1-O-β-D-glucopyranosyl-(2S,3R,8E)-2-[(2R)-2-hydroxylpalmitoylamino]-8-octadecene-1,3-diol (7), 1-O-β-D-glucopyranosyl-(2S,3R,4E,8E)-2-[(2R)-2-hydroxyhexadecanoylaino]-8-octadecene-1,3-diol (8), cerebroside D (9), and cerebroside C (10). Compound 6 was reported as a natural product and all of these compounds were obtained from Fusarium solani for the first time.