海南产木薯茎化学成分研究
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国家973计划项目(2010CB126606);中央级科研院所基本科研业务费专项基金(ITBBZD2007-4-1)资助


Chemical Constituents from the Stems of Cassava (Manihot esculenta) in Hainan
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    摘要:

    从木薯(Manihot esculenta Crantz)茎的乙醇提取物中分离得到6个化合物,通过波谱分析,分别鉴定为呋喃(1)、肥牛木素(2)、3-吲哚甲酸(3)、3,9,13-megastigmanetriol (4)、穗花杉双黄酮(5)、yucalexin P-21 (6),其中化合物1~5为首次从该植物中分离得到。用滤纸片琼脂扩散法测定了这些化合物的抗菌活性,结果表明化合物1、3、46对耐甲氧西林金黄色葡萄球菌(MRSA)和金黄色葡萄球菌均有抑制作用。

    Abstract:

    Six compounds were isolated from the EtOH extract of Manihot esculenta (cassava) stems. On the basis of spectral data, they were identified as furan (1), ceplignan (2), indole-3-carboxylic acid (3), 3,9,13-megastigmanetriol (4), amentoflavone (5) and yucalexin P-21 (6). Compounds 1-5 were obtained from cassava for the first time. Antibacterial activity was assayed by paper disk diffusion method, and compounds 1,3,4, and 6 showed inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus.

    参考文献
    [1] Onwueme I C. Cassava in Asia and the Pacific [M]// Hillocks R J, Tresh J M, Bellotti A C. Cassava: Biology, Production and Utilization. Oxon, New York: CABI Publishing, 2002: 1-55.
    [2] Editorial Committee of Chinese Materia Medica(国家中医药管理局), State Administration of Traditional Chinese Medicine of China(《中华本草》编委会). Chinese Materia Medica Vol. 2 [M]. Shanghai: Shanghai Science and Techonology Press, 1999: 1-464.(in Chinese)
    [3] Kubo I, Masuoka N, Nihei K I, et al. Maniξoba: A quercetin-rich Amazonian dish [J]. J Food Comp Anal, 2006, 19(6/7): 579-588.
    [4] Blagbrough I S, Bayoumi S A L, Rowanet M G, et al. Cassava: An appraisal of its phytochemistry and its biotechnological prospects [J]. Phytochemistry, 2010, 71(17/18): 1940-1951.
    [5] Xu S Y(徐叔云), Bian R L(卞如濂), Chen X(陈修). Methods of pharmacology experiment [M]. Beijing: People’s Sanitation Press, 1982: 1-651.(in Chinese)
    [6] Mei W L(梅文莉), Dai H F(戴好富), Wu D G(吴大刚). A new norneolignan from Cephalomappa sinensis [J]. Chem J Chin Univ(高等学校化学学报), 2006, 27(8): 1480-1481.(in Chinese)
    [7] Li D L(李冬利), Li X M(李晓明), Cui C M(崔传明), et al. Chemical constituents of Hypocreales sp.: An endophytic fungus derived from the red alga Symphyocladia latiuscula [J]. Mar Sci(海洋科学), 2008, 32(11): 51-55.(in Chinese)
    [8] Nakanishi T, Konishi M, Murata H, et al. Phytochemical studies on meliaceous plants: VII. The structures of two new ionone glucosides from Melia toosendan Sieb. et Zucc. and a novel type of selective biooxidation by a kind of protease [J]. Chem Pharm Bull, 1991, 39(10): 2529-2533.
    [9] Sueyoshi E, Liu H, Matsunami K, et al. Bridelionosides A-F: Megastigmane glucosides from Bridelia glauca f. balansae [J]. Phytochemistry, 2006, 67(22): 2483-2493.
    [10] Feng W S, Zhu B, Zheng X K, et al. Chemical constituents of Selaginella stautoniana [J]. Chin J Nat Med, 2011, 9(2): 108-111.
    [11] Sakai T, Nakagawa Y. Diterpenic stress metabolites from cassava roots [J]. Phytochemistry, 1988, 27(12): 3769-3779.
    [12] Pan X L, Tan N H, Zeng G Z, et a1. Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B [J]. Bioorg Med Chem, 2005, 13(20): 5819-5825.
    [13] Lin Y M, Flavin M T, Schure R, et al. Antiviral activities of biflavonoids [J]. Planta Med, 1999, 65(2): 120-125.
    [14] Hyun J J, Woo S S, Yeo S H, et al. Antifungal effect of amentoflavone derived from Selaginella tamariscina [J]. Arch Pharm Res, 2006, 29(9): 746-751.
    [15] Yin M H, Kang D G, Choi D H, et a1. Screening of vasorelaxant activity of some medicinal plants used in Oriental medicines [J]. J Ethnopharmacol, 2005, 99(1): 113-117.
    [16] Cardoso C R P, de Syllos C I M, Bernardi C C, et a1. Mutagcnic activity promoted by amentoflavone and methanolic extract of Byrsonima crassa Niedenzu [J]. Toxicology, 2006, 225(1): 55-63.
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李姗姗,戴好富,赵友兴,左文健,李小娜,梅文莉.海南产木薯茎化学成分研究[J].热带亚热带植物学报,2012,20(2):197~200

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  • 收稿日期:2011-07-06
  • 最后修改日期:2011-09-06
  • 录用日期:2011-10-24
  • 在线发布日期: 2012-03-20
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