石松非生物碱成分研究

Non-alkaloid Constituents from Lycopodium japonicum

摘要:

用层析方法从石松(Lycopodium japonicum)全草的乙醇提取物中分离得到8个化合物。通过波谱分析，分别鉴定为3β,21β,24-trihydroxyserrat-14-烯-16-酮(1)、3α,21β,24-trihydroxyserrat-14-烯-16-酮(2)、3β,21β,24-trihydroxyserrat-14-烯(3)、3α,21β,24-trihydroxyserrat-14-烯(4)、onocerin (5)、豆甾-5-烯-3β,7α-二醇(6)、豆甾-5-烯-3β,7β-二醇(7)和β-谷甾醇(8)。其中化合物1为新化合物，化合物3、4、6、7为首次从该植物中分离获得，化合物2的波谱数据系首次报道。

Abstract:

Eight compounds were isolated from the ethanol extract of Lycopodium japonicum. On the basis of spectral data, they were identified as 3β,21β,24-trihydroxyserrat-14-en-16-one (1), 3α,21β,24-trihydroxyserrat-14-en-16-one (2), 3β,21β,24-trihydroxyserrat-14-en (3), 3α,21β,24-trihydroxyserrat-14-en (4), onocerin (5), stigmasta-5-en-3β,7α-diol (6), stigmasta-5-en-3β,7β-diol (7), β-sitosterol (8). Compound 1 was a new compound, and compounds 3, 4, 6, 7 were obtained from this species for the first time, and the spectral data of compound 2 was reported for the first time.