Abstract:Algicides, bromogeramine(B)and isothiazolone(I),were used for removing Phaeoecystis globosa in the experiments in containers of 450 ml seawater with 109 cells L-1 of algae collected in April 2005 from Zhanjiang Seaport, Guangdong Province, where red tide had happened in January 2004. The results showed that LC50 of isothiazolone was 0.54 mg L-1 for the algae treated for 72 hours, which was more effective than that of bromogeramine (LC50=0.96 mg L-1). Alga-removal effects of both algicides used in combination showed synergistic action. The proportion ofbromogeramine to isothiazolone being 4.3 to 1 gave best result. Toxicity tests on little fishes (Mugil cephdus) showed that 2.0 mg L-1 bromogeramine or 0.3 mg L-1 isothiazolone were safe for fishes in the removal of algae in 72 hours.