板蓝根中甙类成分的研究

Glycosides from the Roots of Baphicacanthus cusia

摘要:

从板蓝(Baphicacanthuscusia(Nees) Bremek.)根甲醇提取物的正丁醇萃取部分中分离鉴定了4个甙类成分,分别为(2R)-2-O-β-D-吡喃葡萄糖基- 1,4-苯并噁嗪-3-酮(1)、(2R)-2-O-β-D-吡喃葡萄糖基-4-羟基-1,4-苯并噁嗪-3-酮(2)、松脂酚-4-O-β-D-芹菜糖基- (1→2)-β-D-吡喃葡萄糖甙(3) 和尿苷。这些化合物均为首次从板蓝根中发现。板蓝根中存在苯并噁嗪酮衍生物(1和2)可能与其消炎作用有关。

Abstract:

Four glycosides, (2R)-2-O-β-D-glucopyranosyl-2H-1,4-benzoxazin-3(4H)- one (1), (2R)-2-O-β-D-glucopyranosyl-4-hydroxy-2H-1,4-benzoxazin-3(4H)-one (2), pinoresinol-4-O-β-D-apiosyl-(1→2)-β-D-glucopy-ranoside (3), and uridine, were isolated from the roots of Baphicacanthus cusia (Nees) Bremek. All these constituents are reported from this plant for the first time. The presence of benzoxazinoids (1 and 2) is in agreement with the anti-inflammatory effect of this plant.