闽产前胡根挥发油的化学成分及其抑菌活性

Chemical Constituents of the Volatile Oil f rom the Roots of Peucedanum praeruptorum and Its Antibacterial Activities

摘要:

采用GC-MS技术分析了闽产前胡(PeucedanumpraeruptorumDunn)根挥发油的化学组成,共鉴定了38种化学成分并测定其相对含量,占总含量的77.97%。其中,β-水茴香萜(9.52%)、α-没药醇(8.44%)、β-蒎烯(5.22%)为主要成分。此外,倍半萜及其氧化物如石竹烯(2.62%)、长叶烯(2.36%)及Z-9-十五烯醇(3.72%)含量也较多。对4种供试病原菌的体外抑菌实验表明,该挥发油对大肠杆菌、伤寒杆菌和弗氏志贺氏菌有一定的抑制或杀灭能力。

Abstract:

The composition of the volatile oil from the roots of Peuc edanum praeruptorum Dunn in Fujian province were analyzed by m eans of GC-MS technique, and 38 chemical constituents, 77.97% of total content, were identified. The main components were a-phellandrene(9.52%),á-bisabolol (8 .44%) anda-pinene (5.22%). Besides, some sesquiterpenes and their oxides such a s caryophyllene (2.62%),longifolene(2.36%) and Z-9-pentadecenol (3.72%) were al so important. The antibacterial experiments of the oil were studied on 4 tested strains in vitro， which showed that the oil had a certain an tibacterial activity against Eschedchm coli，Salmonella typhi and Shigella flexneri.