疏毛吴茱萸化学成分的研究

Chemical Constituents of Near Ripe Fruits of Evodia rutaecarpa var. bodinieri

摘要:

从疏毛吴茱萸干燥近成熟果实的95%乙醇提取物中分离得到8个化合物，经谱学数据分析并与文献报道的数据进行比较，确定其分别为：吴茱萸次碱(1)，吴茱萸碱(2)，7β-羟基吴茱萸次碱(3)，N14-甲酰二氢吴茱萸次碱(4)，去氢吴茱萸碱(5)，吴茱萸果酰胺-I(6)，胡萝卜苷(7)和金丝桃苷(8)。其中，化合物3，4，6~8为首次从该植物中分离得到。

Abstract:

Eight compounds, rutaecarpine (1), evodiamine (2), 7β-hydroxyrutaecarpine (3), N14-formyl dihydrorutaecarpine (4), dehydroevodiamine (5), wuchuyuamide-I (6), daucosterol (7) and hyperoside (8) were isolated from ethanolic extract of the dried and near ripe fruits of Evodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang. Their chemical structures were determined on the basis of spectroscopic evidence (IR, UV, MS, 1D and 2D NMR) and comparison of their spectral data with those of the literatures. Compounds 3, 4, 6~8 were isolated from the titled plants for the first time.